Anxiety symptoms are the strongest predictor of quality of life in temporal lobe epilepsy

PurposeIt is established that the severity of depressive and anxiety symptoms associated with poorer quality life (QOL) in persons drug-resistant epilepsy. We aimed to verify presence subsyndromic episodes (SDEs) (SAEs) temporal lobe epilepsy hippocampal sclerosis (TLE-HS) compared healthy controls determine impact on patients' QOL.MethodsWe prospectively evaluated 35 TLE-HS 90 controls. QOL was assessed by Epilepsy Surgery Inventory (ESI) Inventory-31 (QOLIE-31). The Beck Depression (BDI) State-Trait Anxiety (STAI-X) were used assess symptoms, SDEs SAEs diagnosis made considering total scores BDI (<9) STAI-Trait (<49), respectively.ResultsPersons had higher BDI, STAI-S, STAI-T. They have 3.011 greater odds presenting 7.056 times odds, SAEs. added model epilepsy-related factors, accounted for a significant increase variance several aspects QOL. Anxiety-trait are most critical individual determinant QOL.ConclusionOur results demonstrated SDE SAE than Besides, there relationship between worse TLE-HS. It essential be aware psychiatric even though these do not meet criteria considered "disorder."